National Institute on Drug Abuse Grant: Investigating Inflammasomes in Substance Abuse and HIV

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This grant aims to fund research exploring the role of inflammasomes in the neuro effects of drug exposure and HIV. By investigating inflammasomes’ impact on immune activation, researchers may pinpoint biomarkers related to HIV in substance abuse groups. Additionally, this research could lead to innovative treatments for neuroinflammation and immune dysregulation in these populations. Applications close on March 15, 2023.

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Opportunity ID: 344374

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: RFA-DA-24-004
Funding Opportunity Title:: Targeting Inflammasomes in Substance Abuse and HIV (R21 Clinical Trial Not Allowed)
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 93.279 — Drug Abuse and Addiction Research Programs
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 1
Posted Date:: Nov 03, 2022
Last Updated Date:: Nov 03, 2022
Original Closing Date for Applications:: Mar 15, 2023
Current Closing Date for Applications:: Mar 15, 2023
Archive Date:: Apr 20, 2023
Estimated Total Program Funding::
Award Ceiling:: $
Award Floor:: $

Eligibility

Eligible Applicants:: For profit organizations other than small businesses
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name:: National Institutes of Health
Description:: The scientific objective of this Funding Opportunity Announcement is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat neuroinflammation and immune dysregulation aroused in these processes.
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 1 Nov 03, 2022

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID: FORMS-H
Competition Title: Use for due dates on or after January 25, 2023
Opportunity Package ID: PKG00277929
Opening Date: Feb 15, 2023
Closing Date: Mar 15, 2023
Agency Contact Information:: eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V5.0]
PHS 398 Cover Page Supplement [V5.0]
Research And Related Other Project Information [V1.4]
Project/Performance Site Location(s) [V4.0]
Research and Related Senior/Key Person Profile (Expanded) [V4.0]
PHS 398 Research Plan [V5.0]
PHS Human Subjects and Clinical Trials Information [V3.0]
optional_forms Research & Related Budget [V3.0]
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V3.0]
PHS 398 Modular Budget [V1.2]
PHS Assignment Request Form [V3.0]

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Packages

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Who Can Apply:
FORMS-H Use for due dates on or after January 25, 2023 PKG00277929 Feb 15, 2023 Mar 15, 2023 View eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ Organization Applicants

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