PAR-24-082 Grant Announcement: NIH Funds Research in Childhood Cancers and Birth Defects Under Gabriella Miller Kids First Program

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The National Institutes of Health (NIH) has released a grants notice for a significant research initiative titled “Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)”, under the funding opportunity number PAR-24-082. Announced on December 12, 2023, this discretionary funding opportunity is part of the Gabriella Miller Kids First Pediatric Research Program, aimed at elucidating the genetic contributions to childhood cancers and structural birth defects.

The NIH is inviting applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program-supported sequencing center. This initiative encourages the sequencing of existing pediatric cancer or structural birth defect cohorts to investigate the genetic etiology and the molecular basis of the associations between birth defects and increased cancer risk. The program is particularly interested in proposals that focus on cohorts of underrepresented racial and ethnic groups or aim to increase racial and ethnic representation in existing Kids First Program projects. The data generated, along with associated clinical and phenotypic data, will become part of the Kids First Data Resource Center, making it available for broader research purposes. With the application closing date set for March 13, 2024, this grant represents a significant step towards understanding and addressing pediatric health challenges.

 

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Opportunity ID: 351450

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General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-24-082
Funding Opportunity Title: Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.310 — Trans-NIH Research Support
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Dec 12, 2023
Last Updated Date: Dec 12, 2023
Original Closing Date for Applications: Mar 13, 2024
Current Closing Date for Applications: Mar 13, 2024
Archive Date: Apr 18, 2024
Estimated Total Program Funding:
Award Ceiling: $
Award Floor: $

Eligibility

Eligible Applicants: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
County governments
State governments
City or township governments
Special district governments
Independent school districts
Public housing authorities/Indian housing authorities
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Private institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer or structural birth defect cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of structural birth defects, to study the molecular basis of the associations between birth defects and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts of underrepresented racial and ethnic groups or to increase racial and ethnic representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the research community.
Link to Additional Information: https://grants.nih.gov/grants/guide/pa-files/PAR-24-082.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information
grantsinfo@nih.gov

[/fusion_tab][fusion_tab title=”Related Documents” icon=”” icon_active_color=”” hue=”” saturation=”” lightness=”” alpha=”” icon_color=””]PAR-24-082-Full-Announcement
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