National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism Grants: Investigating Gene-Environment Interplay in Substance Use Disorders (R01)

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This grant opportunity aims to support research on the interplay of genetic and environmental factors in substance and alcohol use disorders. Researchers are encouraged to explore the developmental trajectories of SUDs and comorbid conditions, refine phenotypic definitions, and address methodological challenges in the field. By investigating the contributions of genetics and environment to SUD initiation, progression, and outcomes, this grant seeks to advance knowledge on risk mechanisms and improve treatment and prevention strategies. Applications are welcomed until January 7, 2015.

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Opportunity ID: 106254

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: PA-11-235
Funding Opportunity Title:: Gene-Environment Interplay in Substance Use Disorders (R01)
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 93.273 — Alcohol Research Programs
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 2
Posted Date:: Jul 19, 2011
Last Updated Date:: Jul 31, 2014
Original Closing Date for Applications:: Sep 07, 2014
Current Closing Date for Applications:: Jan 07, 2015
Archive Date:: Feb 07, 2015
Estimated Total Program Funding::
Award Ceiling:: $
Award Floor:: $

Eligibility

Eligible Applicants:: For profit organizations other than small businesses
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Additional Information

Agency Name:: National Institutes of Health
Description:: The National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism seek to stimulate and expand research on the interplay of genetic and environmental factors in the genesis, course, and outcomes of substance and alcohol use disorders (SUDs). Previous work in genetic epidemiology and molecular genetics has established that SUDs are highly heritable, developmental disorders with important genetic substrates. Building on these findings, new studies using genetically informative approaches are needed to elucidate the complex interplay of genetic and environmental factors in developmental trajectories of SUDs and comorbid conditions, deepen and refine phenotypic definitions of SUDs, and meet the methodologic challenges of the field. Such studies hold great potential to promote understanding of the true contributions of both genetic and environmental factors to initiation, progression, comorbidity, adverse outcomes, and desistance of SUDs; to elucidate mechanisms of risk; and to enhance opportunities for translation to treatment, prevention, gene-finding and molecular studies.
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 2 This funding opportunity expiration date is being extended per NOT-DA-14-019. Jul 31, 2014
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID: ADOBE-FORMS-B1
Competition Title: ADOBE-FORMS-B1
Opportunity Package ID: PKG00065091
Opening Date: Sep 05, 2011
Closing Date: Sep 24, 2013
Agency Contact Information:: Grants Info
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V1.2]
Research And Related Other Project Information [V1.3]
Research And Related Senior/Key Person Profile (Expanded) [V1.2]
Project/Performance Site Location(s) [V1.4]
PHS 398 Research Plan [V1.3]
PHS 398 Cover Page Supplement [V1.4]
PHS 398 Checklist [V1.3]
optional_forms Research & Related Budget [V1.1]
R & R Subaward Budget Attachment(s) Form [V1.2]
PHS Cover Letter [V1.2]
PHS 398 Modular Budget [V1.1]

Package No: 2

Assistance Listings:
Competition ID: FORMS-C
Competition Title: Use for due dates after 9/24/2013
Opportunity Package ID: PKG00180515
Opening Date: Sep 08, 2013
Closing Date: Jan 07, 2015
Agency Contact Information:: eRA Commons Help Desk
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V2.0]
PHS 398 Research Plan [V2.0]
PHS 398 Cover Page Supplement [V2.0]
Research and Related Senior/Key Person Profile (Expanded) [V2.0]
Research And Related Other Project Information [V1.3]
Project/Performance Site Location(s) [V2.0]
optional_forms R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3]
Planned Enrollment Report [V1.0]
PHS 398 Cumulative Inclusion Enrollment Report [V1.0]
PHS 398 Modular Budget [V1.2]
Research & Related Budget [V1.3]

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Packages

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Agency Contact Information: Who Can Apply:
ADOBE-FORMS-B1 ADOBE-FORMS-B1 PKG00065091 Sep 05, 2011 Sep 24, 2013 View Grants Info Organization Applicants

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Agency Contact Information: Who Can Apply:
FORMS-C Use for due dates after 9/24/2013 PKG00180515 Sep 08, 2013 Jan 07, 2015 View eRA Commons Help Desk Organization Applicants

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