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The National Institute of Health (NIH) is offering a grant to conduct mechanistic studies on the relationship between alcohol drinking, alcohol dependence, and pain. Researchers will investigate the genetic, pharmacological, and learning mechanisms that underlie the association between alcohol consumption and pain responses. The goal is to understand how chronic pain conditions influence alcohol use patterns and contribute to the development of dependence and addiction. This grant aims to shed light on the overlapping neural substrates of pain transmission and alcohol’s reinforcing effects, revealing how alcohol abuse and dependence may impact individuals experiencing chronic pain.
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Opportunity ID: 106754
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PA-11-268 |
| Funding Opportunity Title:: | Mechanistic Studies of Pain and Alcohol Dependence (R21) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Jul 20, 2011 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Sep 07, 2014 |
| Current Closing Date for Applications:: | Sep 07, 2014 |
| Archive Date:: | Oct 08, 2014 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $200,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Small businesses |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | This Funding Opportunity Announcement (FOA) encourages applications that propose to conduct mechanistic studies on the relationship between alcohol drinking, alcohol dependence and pain. An association between chronic pain conditions and alcohol dependence has been revealed in numerous studies with episodes of alcohol abuse antedating chronic pain in some people and alcohol dependence emerging after the onset of chronic pain in others. Pain transmission and alcohols reinforcing effects share overlapping neural substrates giving rise to the possibility that chronic pain states significantly affect alcohol use patterns and promote the development of dependence and addiction. In addition, long term alcohol intoxication and alcohol dependence induce pain symptoms and may exacerbate chronic pain arising from other sources. The objective of this FOA is to understand genetic, pharmacological and learning mechanisms underlying the association between the propensity to drink alcohol and pain responses. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.273 |
| Competition ID: | ADOBE-FORMS-B1 |
| Competition Title: | ADOBE-FORMS-B1 |
| Opportunity Package ID: | PKG00065550 |
| Opening Date: | Sep 16, 2011 |
| Closing Date: | Sep 24, 2013 |
| Agency Contact Information:: | Grants Info |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Project/Performance Site Location(s) [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Cover Page Supplement [V1.4] PHS 398 Checklist [V1.3] |
| optional_forms |
Research & Related Budget [V1.1] R & R Subaward Budget Attachment(s) Form [V1.2] PHS Cover Letter [V1.2] PHS 398 Modular Budget [V1.1] |
Package No: 2
| Assistance Listings: | 93.273 |
| Competition ID: | FORMS-C |
| Competition Title: | Use for due dates after 9/24/2013 |
| Opportunity Package ID: | PKG00181451 |
| Opening Date: | Sep 16, 2013 |
| Closing Date: | Sep 07, 2014 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Agency Contact Information: | Who Can Apply: |
|---|---|---|---|---|---|---|---|---|
| 93.273 | ADOBE-FORMS-B1 | ADOBE-FORMS-B1 | PKG00065550 | Sep 16, 2011 | Sep 24, 2013 | View | Grants Info | Organization Applicants |
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Agency Contact Information: | Who Can Apply: |
|---|---|---|---|---|---|---|---|---|
| 93.273 | FORMS-C | Use for due dates after 9/24/2013 | PKG00181451 | Sep 16, 2013 | Sep 07, 2014 | View | eRA Commons Help Desk | Organization Applicants |
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