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NINDS is offering a grant to support the preclinical development and testing of new therapies for neurological disorders. This grant focuses on accelerating the translation of basic research discoveries into therapeutic candidates for clinical testing. Projects must include therapeutic leads and in vivo proof of concept on efficacy, with the aim of submitting applications to the FDA by the project end. Excluding early-stage therapeutic discovery activities, clinical research, basic research, and disease mechanism studies, this program emphasizes therapy development activities. NINDS staff actively participate in project planning and research progress monitoring in this milestone-driven cooperative agreement program.
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Opportunity ID: 112214
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PAR-11-294 |
| Funding Opportunity Title:: | NINDS Cooperative Program in Translational Research Single-Component Research Projects (U01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 2 |
| Posted Date:: | Aug 08, 2011 |
| Last Updated Date:: | Apr 10, 2012 |
| Original Closing Date for Applications:: | Sep 07, 2012 |
| Current Closing Date for Applications:: | Jan 07, 2013 |
| Archive Date:: | Feb 07, 2013 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | County governments |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The goal of this funding opportunity announcement (FOA) is to support preclinical development and testing of new therapies for neurological disorders. The program will facilitate encouragement , development, and review of therapy-directed projects to accelerate the translation of basic research discoveries into therapeutic candidates for clinical testing. To be eligible for support, projects must include therapeutic leads and in vivo proof of concept on efficacy. The program supports preclinical optimization and testing of the leads, and projects must be sufficiently advanced that an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application to the Food and Drug Administration (FDA) can be submitted by the end of the project period. The program does not support early-stage therapeutic discovery activities such as screening. The program also excludes clinical research, basic research, and studies of disease mechanism. The scope includes only therapy development activities, so development of diagnostics, biomarkers, or rehabilitation strategies cannot be supported. This is a milestone-driven cooperative agreement program involving participation of NINDS staff in the development of the project plan and monitoring of research progress. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 2 | Modified Archive Date based on new Expiration Date of January 8, 2013. | Apr 10, 2012 |
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.853 |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | Adobe-Forms-B2 |
| Opportunity Package ID: | PKG00070051 |
| Opening Date: | Sep 05, 2011 |
| Closing Date: | Jan 07, 2013 |
| Agency Contact Information:: | Grants Info |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Agency Contact Information: | Who Can Apply: |
|---|---|---|---|---|---|---|---|---|
| 93.853 | ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00070051 | Sep 05, 2011 | Jan 07, 2013 | View | Grants Info | Organization Applicants |
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