The National Cancer Institute is offering a research grant to study the impact of Erythropoiesis Stimulating Agents (ESAs) like Erythropoietin (EPO) on tumor growth. With concerns over ESAs potentially accelerating tumor progression and increasing mortality in cancer patients, this grant aims to support research on the effects of ESAs on tumor biology and progression. Utilizing the NIH Exploratory/Developmental Grant (R21) mechanism, this opportunity encourages high-quality projects to enhance understanding of how ESAs influence tumor cell growth and apoptosis. The grant seeks to address crucial questions regarding the relationship between ESAs and cancer development.
Opportunity ID: 43318
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-09-024 |
| Funding Opportunity Title: | Erythropoiesis Stimulating Agents and Tumor Progression (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 06, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2012 |
| Current Closing Date for Applications: | Jan 07, 2012 |
| Archive Date: | Feb 07, 2012 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments For profit organizations other than small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Independent school districts Private institutions of higher education City or township governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -Purpose. This funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), invites applications for research projects that investigate the effects of Erythropoietin (EPO) on tumor cell growth. EPO has been widely used to relieve the anemia associated with renal failure. In addition, EPO and other erythropoiesis stimulating agents (ESAs) have recently been used to treat the anemia associated with cancer chemotherapy. However, several clinical trials involving administration of ESAs, have suggested that ESAs may accelerate tumor progression and increase mortality in cancer patients. It is therefore important to understand the biology of ESAs on tumor cell growth and apoptosis. The purpose of this FOA is to stimulate high quality research on the effects of ESAs on tumor cell biology and tumor progression. -Mechanism of Support. This FOA utilizes the NIH Exploratory/Developmental Grant (R21) mechanism and runs in parallel with an FOA of identical scientific scope, PA-09-023 that encourages applications under the NIH Research Project Grant (R01) mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications; therefore, the anticipated number of awards is not known |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-09-024.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00009527 | Jan 16, 2009 | Feb 20, 2010 | View | |
| ADOBE-FORMS-B1 | Supersedes ADOBE-FORMS-B | PKG00022250 | Nov 02, 2010 | Jan 07, 2012 | View | |
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00015344 | Dec 21, 2009 | Nov 02, 2010 | View |
Package 1
Mandatory forms
43318 RR_SF424-1.1.pdf
43318 RR_KeyPersonExpanded-1.1.pdf
43318 RR_OtherProjectInfo-1.1.pdf
43318 RR_PerformanceSite-1.1.pdf
43318 PHS398_CoverPageSupplement-1.1.pdf
43318 PHS398_ResearchPlan-1.1.pdf
43318 PHS398_Checklist-1.1.pdf
Optional forms
43318 PHS398_CoverLetter-1.1.pdf
43318 PHS398_ModularBudget-1.1.pdf
43318 RR_Budget-1.1.pdf
43318 RR_SubawardBudget-1.2.pdf
Package 2
Mandatory forms
43318 RR_SF424_1_2-1.2.pdf
43318 RR_OtherProjectInfo_1_3-1.3.pdf
43318 RR_KeyPersonExpanded_1_2-1.2.pdf
43318 PerformanceSite_1_4-1.4.pdf
43318 PHS398_ResearchPlan_1_3-1.3.pdf
43318 PHS398_CoverPageSupplement_1_4-1.4.pdf
43318 PHS398_Checklist_1_3-1.3.pdf
Optional forms
43318 RR_Budget-1.1.pdf
43318 RR_SubawardBudget-1.2.pdf
43318 PHS_CoverLetter_1_2-1.2.pdf
43318 PHS398_ModularBudget-1.1.pdf
Package 3
Mandatory forms
43318 RR_SF424_1_2-1.2.pdf
43318 PerformanceSite_1_3-1.3.pdf
43318 RR_OtherProjectInfo_1_2-1.2.pdf
43318 RR_KeyPersonExpanded_1_2-1.2.pdf
43318 PHS398_CoverPageSupplement_1_4-1.4.pdf
43318 PHS398_ResearchPlan_1_3-1.3.pdf
43318 PHS398_Checklist_1_3-1.3.pdf
Optional forms
43318 PHS_CoverLetter_1_2-1.2.pdf
43318 PHS398_ModularBudget-1.1.pdf
43318 RR_Budget-1.1.pdf
43318 RR_SubawardBudget-1.2.pdf
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