NHGRI is offering a grant to analyze the full dataset generated by the international 1000 Genomes Project. The project aims to create a comprehensive resource on human genetic variation for genome-wide association studies and other research. This grant seeks proposals to characterize the dataset, study allele frequency distribution, identify signals of natural selection, develop new data types, evaluate dataset development strategies, and create tools for data analysis. Researchers are encouraged to apply their findings to genome-wide association studies. Closing date for grant applications is June 26, 2009.
Opportunity ID: 43589
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-09-002 |
| Funding Opportunity Title: | 1000 Genomes Project Dataset Analysis (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 04, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 26, 2009 |
| Current Closing Date for Applications: | Jun 26, 2009 |
| Archive Date: | Jul 27, 2009 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign institutions are not eligible for awards under this program, as primary awardees or under subcontracts. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. The international 1000 Genomes Project is designed to produce a new high-resolution resource on human genetic variation to support genome-wide association studies and other studies of human disease and biology. The primary source of data will be light sequencing of the genomes of about 1200-1500 anonymized individuals. These data should be sufficient to find most DNA sequence variants in the human population that have a frequency of 1% or more. Several large-scale sequencing centers, including three funded by NHGRI, are involved in this international effort. Currently pilot projects are underway to assess the sequencing platforms and provide data that will be used to design the full-scale project. By the end of 2008 the full-scale project should be underway; it is expected to take about two years and produce about 20 Terabases of sequence data. The Project regularly will release raw sequence data and data derived from the sequence data, such as genotype calls for single-nucleotide polymorphisms (SNPs) and structural variants, and their linkage disequilibrium patterns. This FOA solicits proposals to characterize and analyze the full dataset, such as for allele frequency distribution and signals of natural selection, to produce additional data types, to evaluate the strategies used to develop the dataset, and to develop the tools needed to work with the data and apply them to other studies such as genome-wide association studies. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-09-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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