The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Child Health and Human Development are offering a research grant aimed at advancing knowledge on HIV transmission in semen. This grant supports studies on factors influencing HIV shedding in the male genital tract, including infectivity in semen fractions, effects of antiretroviral therapy, and the impact of genital tract inflammation. Researchers are encouraged to explore virus-infected cells, virus production sites, and the immunobiology of the male genital tract. The grant aims to foster innovative research, attract new investigators, and promote interdisciplinary collaborations in this critical area of HIV research.
Opportunity ID: 43776
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-07-044 |
| Funding Opportunity Title: | Transmission of Human Immunodeficiency Virus (HIV) In Semen (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.849 — Kidney Diseases, Urology and Hematology Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Current Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Apr 05, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments City or township governments Special district governments For profit organizations other than small businesses Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) through its Division of Kidney, Urologic and Hematologic Diseases (DKUHD) and the National Institute of Child Health and Human Development, Center for Population Research invite investigators to submit research grant applications that will increase the basic and clinical knowledge of the biology of HIV in semen. Direct exposure to semen of HIV seropositive men is a major route for transmission of HIV type I. This Funding Opportunity Announcement (FOA) focuses on studies that will elucidate the factors that determine HIV shedding in the male genital tract. This includes studies that elucidate the infectivity of HIV in semen fractions, the effect of antiretroviral therapy on HIV infectivity in semen fractions, the relationship between the immunobiology of the male genital tract and HIV replication and infectivity, and factors such as genital tract inflammation which influence HIV transmission through semen. Of particular interest are studies of the anatomic sites of virus infected cells and virus production in the male genital tract. The intent of this Funding opportunity is to encourage investigator-initiated research, to attract new investigators to the field, and to increase interdisciplinary research to enhance the scope and effectiveness of research in this area. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-07-044.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00009124 | Dec 05, 2008 | Mar 06, 2009 | View |
Package 1
Mandatory forms
43776 RR_SF424-1.1.pdf
43776 RR_KeyPersonExpanded-1.1.pdf
43776 RR_OtherProjectInfo-1.1.pdf
43776 RR_PerformanceSite-1.1.pdf
43776 PHS398_CoverPageSupplement-1.1.pdf
43776 PHS398_ResearchPlan-1.1.pdf
43776 PHS398_Checklist-1.1.pdf
Optional forms
43776 PHS398_CoverLetter-1.1.pdf
43776 PHS398_ModularBudget-1.1.pdf
43776 RR_Budget-1.1.pdf
43776 RR_SubawardBudget-1.2.pdf
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