The National Cancer Institute is offering the Correlative Studies with Specimens from Multi-Site Trials Grant to fund translational research projects utilizing annotated tumor and biospecimens from large multi-institutional trials. The grant aims to predict responses to interventions, inspire therapeutic strategies, and improve drug development. Projects should focus on correlating intervention outcomes with disease characteristics at cellular/molecular levels. This grant only supports studies using tumor specimens linked to specific interventions. Applications should foster collaboration between basic researchers and clinical investigators. The grant operates through the NIH Exploratory/Developmental Grant (R21) mechanism and is closely related to PA-08-134 under the NIH Research Project Grant (R01) mechanism. Closing date for applications is May 07, 2011.
Opportunity ID: 44073
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-08-133 |
| Funding Opportunity Title: | Correlative Studies with Specimens from Multi-Site Trials (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | May 07, 2011 |
| Current Closing Date for Applications: | May 07, 2011 |
| Archive Date: | Jun 07, 2011 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Small businesses State governments |
| Additional Information on Eligibility: |
Other Eligible Applicants include the following: Eligible Agencies of the Federal Government Non-domestic (non-U.S.) Entities (Foreign Organizations) Regional Organizations U.S. Territory or Possession |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -Purpose. This Funding Opportunity Announcement (FOA) is intended to support translational correlative studies that utilize annotated tumor and/or other biospecimens collected during large-scale multi-institutional clinical and/or prevention trials, respectively. The Cancer Therapy Evaluation Program (CTEP), the Cancer Diagnosis Program (CDP), and the Cancer Biomarkers Research Group (CBRG) of the NCI are cooperatively sponsoring this FOA with the overarching goal to facilitate predictions of responses to current interventions, and inspire future development of improved therapeutic and preventive strategies. Projects proposed in response to this FOA should address the correlations between intervention outcomes and cancer patients disease characteristics determined at various cellular/molecular levels. For example, disease progression patterns may be correlated with tumor genotypic and/or phenotypic profiles (at the levels of the genome, epigenome, gene expression and/or protein and non-protein molecular markers. This FOA will only support studies that use tumor specimens linked to specific interventions/trials. To be able to achieve these translational goals, the proposed projects are expected to rely on interactions between basic researchers and clinical investigators, in order to improve future drug development and interventions. -Mechanism of Support. This FOA utilizes the NIH Exploratory/Developmental Grant (R21) mechanism and runs in parallel with an FOA of identical scientific scope, PA-08-134, that solicits applications under the NIH Research Project Grant (R01) mechanism. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-08-133.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00009421 | Dec 05, 2008 | Feb 20, 2010 | View | |
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00015256 | Dec 21, 2009 | May 07, 2011 | View |
Package 1
Mandatory forms
44073 RR_SF424-1.1.pdf
44073 RR_KeyPersonExpanded-1.1.pdf
44073 RR_OtherProjectInfo-1.1.pdf
44073 RR_PerformanceSite-1.1.pdf
44073 PHS398_CoverPageSupplement-1.1.pdf
44073 PHS398_ResearchPlan-1.1.pdf
44073 PHS398_Checklist-1.1.pdf
Optional forms
44073 PHS398_CoverLetter-1.1.pdf
44073 PHS398_ModularBudget-1.1.pdf
44073 RR_Budget-1.1.pdf
44073 RR_SubawardBudget-1.2.pdf
Package 2
Mandatory forms
44073 RR_SF424_1_2-1.2.pdf
44073 PerformanceSite_1_3-1.3.pdf
44073 RR_OtherProjectInfo_1_2-1.2.pdf
44073 RR_KeyPersonExpanded_1_2-1.2.pdf
44073 PHS398_CoverPageSupplement_1_4-1.4.pdf
44073 PHS398_ResearchPlan_1_3-1.3.pdf
44073 PHS398_Checklist_1_3-1.3.pdf
Optional forms
44073 PHS_CoverLetter_1_2-1.2.pdf
44073 PHS398_ModularBudget-1.1.pdf
44073 RR_Budget-1.1.pdf
44073 RR_SubawardBudget-1.2.pdf
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