The Health and Human Services Department is offering the STTR (R41/R42) grant to fund the development of new toxicity assays to predict organ toxicities resulting from exposures to various chemicals, pollutants, therapeutics, and drugs. This grant supports the creation of innovative strategies, assays, and models for assessing organ health, including high throughput screening methods and 3-dimensional organ models. Small businesses can apply for Phase I, Phase II, or Fast-Track funding to advance toxicity evaluation in areas such as ocular, cardiotoxicity, neurotoxicity, and more. Deadline for applications is September 7, 2009.
Opportunity ID: 44976
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-09-007 |
| Funding Opportunity Title: | Innovative Toxicity Assays of Pollutants, Therapeutics, and Drugs (STTR [R41/R42]) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Environment Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 26, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2009 |
| Current Closing Date for Applications: | Sep 07, 2009 |
| Archive Date: | Oct 08, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -Purpose. This Funding Opportunity Announcement (FOA) encourages Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involves the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. -Mechanism of Support. This FOA will utilize the STTR (R41/R42) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-006, that encourages applications under the Small Business Innovation Research (SBIR) (R43/R44) grant mechanisms. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-09-007.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00010186 | Jan 26, 2009 | Sep 07, 2009 | View |
Package 1
Mandatory forms
44976 RR_SF424-1.1.pdf
44976 RR_KeyPersonExpanded-1.1.pdf
44976 RR_OtherProjectInfo-1.1.pdf
44976 RR_PerformanceSite-1.1.pdf
44976 RR_Budget-1.1.pdf
44976 RR_SubawardBudget-1.2.pdf
44976 SBIR_STTR_Information-1.0.pdf
44976 PHS398_CoverPageSupplement-1.1.pdf
44976 PHS398_ResearchPlan-1.1.pdf
44976 PHS398_Checklist-1.1.pdf
Optional forms
44976 PHS398_CoverLetter-1.1.pdf
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