NIDDK Grant: Advancing Inflammatory Bowel Disease Genetics Research

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The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) is seeking Genetic Research Centers (GRCs) to identify susceptibility genes for IBD. This grant aims to continue discovering genetic variants predisposing individuals to IBD and integrating various -omic methodologies to understand their effects on the disease’s pathophysiology. GRCs will enroll IBD patients, relatives, and healthy controls for studies, conducting laboratory-based research on their biological samples. Principal Investigators of GRCs will be part of the IBDGC Steering Committee, making operational decisions for the consortium. Apply before the closing date on Apr 30, 2012, to contribute to advancing IBD genetics research.

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Opportunity ID: 143254

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: RFA-DK-11-032
Funding Opportunity Title:: NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genetic Research Centers (GRCs) (U01)
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Food and Nutrition
Category Explanation::
Expected Number of Awards:: 6
Assistance Listings Number(s):: 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 1
Posted Date:: Feb 09, 2012
Last Updated Date::
Original Closing Date for Applications:: Apr 30, 2012
Current Closing Date for Applications:: Apr 30, 2012
Archive Date:: May 31, 2012
Estimated Total Program Funding:: $ 2,250,000
Award Ceiling:: $250,000
Award Floor:: $

Eligibility

Eligible Applicants:: Small businesses
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name:: National Institutes of Health
Description:: The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) was established in July, 2002 for the purpose of identifying genes predisposing to IBD.Since its establishment, the IBDGC, in collaboration with other international IBD genetics consortia, has identified more than 100 such susceptibility loci.However, many susceptibility genes still remain to be identified, and the work of elucidating how IBD risk-associated genetic variants influence the pathophysiology of IBD has barely begun.The purpose of this FOA is to renew the IBDGC to continue the discovery of susceptibility variants, and to integrate genomic with epigenomic, transcriptomic, proteomic, metabolomic, and other -omic methodologies to elucidate the effects of genetic risk variants on the pathophysiology of IBD.The GRCs will serve as sites of enrollment of IBD patients, relatives, and healthy controls for these studies, and for laboratory-based studies on biological samples taken from these subjects.The PD(s)/PI(s) of the GRCs will serve as members of the Steering Committee of the IBDGC, which will be responsible for all of the IBDGC’s operational decisions, which will be binding upon all of the IBDGC’s members.
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings: 93.847
Competition ID: ADOBE-FORMS-B2
Competition Title: Adobe-Forms-B2
Opportunity Package ID: PKG00096811
Opening Date: Mar 30, 2012
Closing Date: Apr 30, 2012
Agency Contact Information:: Grants Info
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V1.2]
Project/Performance Site Location(s) [V1.4]
Research And Related Other Project Information [V1.3]
Research And Related Senior/Key Person Profile (Expanded) [V1.2]
PHS 398 Cover Page Supplement [V1.4]
PHS 398 Research Plan [V1.3]
PHS 398 Checklist [V1.3]
optional_forms R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2]
PHS 398 Modular Budget [V1.2]
Research & Related Budget [V1.1]
PHS Cover Letter [V1.2]

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Packages

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Who Can Apply:
93.847 ADOBE-FORMS-B2 Adobe-Forms-B2 PKG00096811 Mar 30, 2012 Apr 30, 2012 View Grants Info Organization Applicants

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