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This DARPA grant aims to support the development of processes for rapid synthesis, screening, sequencing, and scaling of folded, non-natural, sequence-defined polymers with enhanced functionality. The focus is on creating non-natural affinity reagents and catalytic systems that can bind to specific targets or synthesize/degrade desired substances. The program seeks novel synthetic approaches to generate large libraries of polymers, efficient screening strategies, rapid selection of binders and catalysts, and scalability for the DoD community. Applicants are encouraged to refer to DARPA-BAA-14-13 for more details. Closing date for applications is April 3, 2014.
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Opportunity ID: 249776
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | DARPA-BAA-14-13 |
| Funding Opportunity Title:: | Folded Non-Natural Polymers with Biological Function (Fold F(x)) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Science and Technology and other Research and Development |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 12.910 — Research and Technology Development |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 3 |
| Posted Date:: | Jan 07, 2014 |
| Last Updated Date:: | Feb 03, 2014 |
| Original Closing Date for Applications:: | Apr 03, 2014 |
| Current Closing Date for Applications:: | Apr 03, 2014 |
| Archive Date:: | Jun 03, 2014 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility:: |
Additional Information
| Agency Name:: | DARPA – Defense Sciences Office |
| Description:: | The DARPA Fold F(x) program objective is to develop processes enabling the rapid synthesis, screening, sequencing and scale-up of folded, non-natural, sequence-defined polymers with expanded functionality. The program will specifically address the development of non-natural affinity reagents that can bind and respond to a selected target, as well as catalytic systems that can either synthesize or degrade a desired target. DARPA anticipates that successful efforts will include (1) novel synthetic approaches that yield large libraries (>109 members) of non-natural sequence-defined polymers; (2) flexible screening strategies that enable the selection of high affinity/specificity binders and high activity/selectivity catalysts from the non-natural libraries; (3) demonstration that the screening approach can rapidly (<4 days) yield affinity reagents or catalysts against targets of interest to the DoD; and (4) demonstration of scalability and transferability to the DoD scientific community.See Attached DARPA-BAA-14-13. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 3 | Modification 2 to DARPA-BAA-14-13, Folded Non-Natural Polymers with Biological Function (Fold F(x)), is to revise language under Program Objectives, Structure and Milestones, Option 1 and update FAQ deadline.
See Modification 2 to DARPA-BAA-14-13 attached. |
Feb 03, 2014 |
| Synopsis 2 | Modification 1 to DARPA-BAA-14-13, Folded Non-Natural Polymers with Biological Function (Fold F(x)), is to change the White Paper Submission Deadline and White Paper and Full Proposal Question and Answer Response Deadline.
See Attached Modification 1 to DARPA-BAA-14-13. |
|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 12.910 |
| Competition ID: | |
| Competition Title: | |
| Opportunity Package ID: | PKG00191591 |
| Opening Date: | Jan 07, 2014 |
| Closing Date: | Apr 03, 2014 |
| Agency Contact Information:: | BAA COORDINATOR |
| Who Can Apply:: | Organization and Individual Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] Attachments [V1.1] |
| optional_forms | Disclosure of Lobbying Activities (SF-LLL) [V1.1] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 12.910 | PKG00191591 | Jan 07, 2014 | Apr 03, 2014 | View | BAA COORDINATOR | Organization and Individual Applicants |
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