DARPA Grant: Developing Folded Non-Natural Polymers for Biological Function

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This DARPA grant aims to support the development of processes for rapid synthesis, screening, sequencing, and scaling of folded, non-natural, sequence-defined polymers with enhanced functionality. The focus is on creating non-natural affinity reagents and catalytic systems that can bind to specific targets or synthesize/degrade desired substances. The program seeks novel synthetic approaches to generate large libraries of polymers, efficient screening strategies, rapid selection of binders and catalysts, and scalability for the DoD community. Applicants are encouraged to refer to DARPA-BAA-14-13 for more details. Closing date for applications is April 3, 2014.

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Opportunity ID: 249776

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: DARPA-BAA-14-13
Funding Opportunity Title:: Folded Non-Natural Polymers with Biological Function (Fold F(x))
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Science and Technology and other Research and Development
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 12.910 — Research and Technology Development
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 3
Posted Date:: Jan 07, 2014
Last Updated Date:: Feb 03, 2014
Original Closing Date for Applications:: Apr 03, 2014
Current Closing Date for Applications:: Apr 03, 2014
Archive Date:: Jun 03, 2014
Estimated Total Program Funding::
Award Ceiling:: $
Award Floor:: $

Eligibility

Eligible Applicants:: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility::

Additional Information

Agency Name:: DARPA – Defense Sciences Office
Description:: The DARPA Fold F(x) program objective is to develop processes enabling the rapid synthesis, screening, sequencing and scale-up of folded, non-natural, sequence-defined polymers with expanded functionality. The program will specifically address the development of non-natural affinity reagents that can bind and respond to a selected target, as well as catalytic systems that can either synthesize or degrade a desired target. DARPA anticipates that successful efforts will include (1) novel synthetic approaches that yield large libraries (>109 members) of non-natural sequence-defined polymers; (2) flexible screening strategies that enable the selection of high affinity/specificity binders and high activity/selectivity catalysts from the non-natural libraries; (3) demonstration that the screening approach can rapidly (<4 days) yield affinity reagents or catalysts against targets of interest to the DoD; and (4) demonstration of scalability and transferability to the DoD scientific community.See Attached DARPA-BAA-14-13.
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 3 Modification 2 to DARPA-BAA-14-13, Folded Non-Natural Polymers with Biological Function (Fold F(x)), is to revise language under Program Objectives, Structure and Milestones, Option 1 and update FAQ deadline.

See Modification 2 to DARPA-BAA-14-13 attached.

Feb 03, 2014
Synopsis 2 Modification 1 to DARPA-BAA-14-13, Folded Non-Natural Polymers with Biological Function (Fold F(x)), is to change the White Paper Submission Deadline and White Paper and Full Proposal Question and Answer Response Deadline.

See Attached Modification 1 to DARPA-BAA-14-13.

Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings: 12.910
Competition ID:
Competition Title:
Opportunity Package ID: PKG00191591
Opening Date: Jan 07, 2014
Closing Date: Apr 03, 2014
Agency Contact Information:: BAA COORDINATOR
Who Can Apply:: Organization and Individual Applicants
mendatory_forms SF424 (R & R) [V2.0]
Attachments [V1.1]
optional_forms Disclosure of Lobbying Activities (SF-LLL) [V1.1]

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Packages

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Who Can Apply:
12.910 PKG00191591 Jan 07, 2014 Apr 03, 2014 View BAA COORDINATOR Organization and Individual Applicants

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