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animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” last=”true” border_position=”all” first=”true”][fusion_alert type=”success” accent_color=”#808080″ hue=”” saturation=”” lightness=”” alpha=”” background_color=”#ffffff” border_size=”” border_radius_top_left=”” border_radius_top_right=”” border_radius_bottom_right=”” border_radius_bottom_left=”” icon=”” text_align=”” padding_top=”” padding_right=”” padding_bottom=”” padding_left=”” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” text_transform=”” link_color_inheritance=”” dismissable=”no” box_shadow=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” logics=””]
NIDDK is offering a grant to support lead optimization and preclinical development of new therapies for diseases falling within its mission. This grant includes Phase I for preliminary steps in the process and Phase II for advanced projects, aiming to submit applications to the FDA. Proposals should outline defined milestones and timelines, with key decision points. Closing date for applications is January 7, 2017.
[/fusion_alert][fusion_text columns=”” column_min_width=”” column_spacing=”” rule_style=”” rule_size=”” rule_color=”” hue=”” saturation=”” lightness=”” alpha=”” content_alignment_medium=”” content_alignment_small=”” content_alignment=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” fusion_font_family_text_font=”” fusion_font_variant_text_font=”” font_size=”” line_height=”” letter_spacing=”” text_transform=”” text_color=”” animation_type=”” animation_direction=”left” animation_color=”” animation_speed=”0.3″ animation_delay=”0″ animation_offset=”” logics=””]
Opportunity ID: 249654
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PA-14-054 |
| Funding Opportunity Title:: | Lead Optimization and Pre-Clinical Development of Therapeutic Candidates for Diseases of Interest to NIDDK (STTR (R41/R42)) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Food and Nutrition |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Jan 02, 2014 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Jan 07, 2017 |
| Current Closing Date for Applications:: | Jan 07, 2017 |
| Archive Date:: | Feb 07, 2017 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Small businesses |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The goal of this Funding Opportunity Announcement (FOA) is to support lead optimization and preclinical development of new therapies for diseases within the mission of the NIDDK. Phase I supports preliminary steps in the process for lead optimization or preclinical development of therapeutics. Phase II supports lead optimization and preclinical development of lead candidates and projects must be sufficiently advanced such that an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application to the Food and Drug Administration (FDA) can be submitted by the end of a Phase II or IIB project. Applications are expected to have defined Milestones and Timelines detailing how the project will move forward with identified key Go/No Go decision points. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.847 |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | Adobe-Forms-B2 |
| Opportunity Package ID: | PKG00191470 |
| Opening Date: | Mar 05, 2014 |
| Closing Date: | Sep 07, 2014 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Research & Related Budget [V1.1] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] SBIR/STTR_Information [V1.1] |
| optional_forms | PHS Cover Letter [V1.2] |
Package No: 2
| Assistance Listings: | |
| Competition ID: | FORMS-C |
| Competition Title: | Use for due dates on or after August 5, 2014 |
| Opportunity Package ID: | PKG00196573 |
| Opening Date: | Mar 05, 2014 |
| Closing Date: | Jun 08, 2016 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] SBIR/STTR_Information [V1.1] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Research & Related Budget [V1.3] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Project/Performance Site Location(s) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] |
| optional_forms |
Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] |
Package No: 3
| Assistance Listings: | |
| Competition ID: | FORMS-D |
| Competition Title: | Use for due dates on or after May 25, 2016 |
| Opportunity Package ID: | PKG00224045 |
| Opening Date: | Aug 05, 2016 |
| Closing Date: | Jan 07, 2017 |
| Agency Contact Information:: | eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Cover Page Supplement [V3.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research & Related Budget [V1.3] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] PHS 398 Research Plan [V3.0] SBIR/STTR_Information [V1.1] |
| optional_forms |
PHS Inclusion Enrollment Report [V1.0] PHS Assignment Request Form [V1.0] |
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