NIH Launches Grant for Revolutionary Inner Ear Imaging Technology

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The National Institutes of Health (NIH) has announced a new funding opportunity, RFA-DC-24-005, focusing on the advancement of in vivo high-resolution imaging technologies for visualizing the human inner ear. This cooperative agreement, titled “Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required),” aims to elevate the standards of auditory and vestibular component imaging. With an award ceiling of $500,000, this initiative invites a diverse range of applicants, including higher education institutions, nonprofits, government entities, and small businesses, to propose projects that enhance or develop innovative imaging techniques. The projects should focus on capturing detailed and accurate images of inner ear structures in living humans, an advancement that could revolutionize the diagnosis and treatment of deafness and communication disorders.

Key to this funding opportunity is the development of non-invasive techniques that can visualize dynamic elements of the inner ear, such as hair cells and otoliths, in awake patients. This breakthrough research, expected to culminate by February 2025, will require a multidisciplinary approach, leveraging the expertise of various specialists. The successful projects will not only push the boundaries of current imaging capabilities but also pave the way for significant improvements in clinical practices related to auditory and vestibular health.

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Opportunity ID: 350947

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General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DC-24-005
Funding Opportunity Title: Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.173 — Research Related to Deafness and Communication Disorders
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Nov 09, 2023
Last Updated Date: Nov 09, 2023
Original Closing Date for Applications: Feb 03, 2025
Current Closing Date for Applications: Feb 03, 2025
Archive Date: Mar 11, 2025
Estimated Total Program Funding:
Award Ceiling: $500,000
Award Floor: $

Eligibility

Eligible Applicants: Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Independent school districts
Native American tribal organizations (other than Federally recognized tribal governments)
Native American tribal governments (Federally recognized)
Small businesses
County governments
Special district governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Public housing authorities/Indian housing authorities
City or township governments
Private institutions of higher education
State governments
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: This funding opportunity aims to support high risk clinical trials for the development of in vivo high-resolution structural and functional imaging technologies for the living human inner ear. Proposed projects should focus on improving the resolution of current imaging techniques or developing new imaging techniques that can visualize inner ear structures in vivo with significantly greater detail and accuracy than currently possible. Structural and functional aspects, including visualizing dynamic elements, are important to developing new and improved techniques. Projects may also focus on developing new imaging probes or contrast agents that can enhance visualization of the inner ear structures. Research supported in response to this RFA is expected to significantly advance the ability to visualize auditory and vestibular components, such as hair cells, otoliths, membranes, ions, and vasculature, in detail in awake patients in a clinical setting using non-invasive techniques. To achieve this goal, a multidisciplinary team approach that takes advantage of the expertise of each team member is highly encouraged. Studies in humans must be proposed to develop,advance, or test the needed technology. Any intermediate studies must articulate a clear path of the proposed methodology to application in awake humans or define the limitations and the usefulness in anesthetized humans.
Link to Additional Information: https://grants.nih.gov/grants/guide/rfa-files/RFA-DC-24-005.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information
grantsinfo@nih.gov

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[/fusion_tab][fusion_tab title=”Related Documents” icon=”” icon_active_color=”” hue=”” saturation=”” lightness=”” alpha=”” icon_color=””]RFA-DC-24-005-Full-Announcement
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