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This grant opportunity from the National Heart, Lung, and Blood Institute seeks to fund a Data Coordinating Center for the Pulmonary Vascular Disease Phenomics Program. The program aims to identify novel subclassifications of pulmonary hypertension patients through comprehensive phenotyping, leading to better understanding of the disease’s molecular mechanisms. The research conducted is intended to discover biomarkers that could aid early diagnosis and treatment interventions. Applications for the Data Coordinating Center are being solicited in conjunction with a separate call for Clinical Centers. The grant supports deep phenotyping efforts across pulmonary hypertension clinical groups to redefine pulmonary vascular diseases.
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Opportunity ID: 248301
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-HL-14-030 |
| Funding Opportunity Title:: | Redefining Pulmonary Hypertension through Pulmonary Vascular Disease Phenomics: Data Coordinating Center (DCC) (U01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.838 — Lung Diseases Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Nov 25, 2013 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Jan 29, 2014 |
| Current Closing Date for Applications:: | Jan 29, 2014 |
| Archive Date:: | Mar 01, 2014 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $275,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Independent school districts |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The purpose of this funding opportunity announcement (FOA) is to invite applications to participate in a new NHLBI Pulmonary Vascular Disease Phenomics Program (hereafter referred to as “PVDOMICS”). Teams of investigators will perform comprehensive, deep phenotyping across the current World Health Organization (WHO)-classified pulmonary hypertension (PH) clinical Groups 1 through 5 (http://www.nhlbi.nih.gov/health/health-topics/topics/pah/types.html), which will lead to novel subclassifications of patients with pulmonary vascular-right ventricular disease, based on molecular and radiographic as well as clinical characteristics, which can be associated with specific molecular mechanisms of pathogenesis. This research is intended to lead to identification of both endophenotypes of lung vascular disease and biomarkers of disease that may be useful for early diagnosis or for assessment of interventions to prevent or treat this condition. This FOA solicits applications for the Data Coordinating Center (DCC) and runs in parallel with a separate FOA that solicits applications for the Clinical Centers (CCs) (RFA HL-14-027). The common phenotyping protocol will be aimed at: |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.838 |
| Competition ID: | FORMS-C |
| Competition Title: | Forms-C |
| Opportunity Package ID: | PKG00190150 |
| Opening Date: | Dec 29, 2013 |
| Closing Date: | Jan 29, 2014 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.838 | FORMS-C | Forms-C | PKG00190150 | Dec 29, 2013 | Jan 29, 2014 | View | eRA Commons Help Desk | Organization Applicants |
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