National Institute of Diabetes and Digestive and Kidney Diseases Grant: Consortium for Chronic Pancreatitis Research

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The National Institute of Diabetes and Digestive and Kidney Diseases is offering a grant to establish a clinical consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer. This grant aims to conduct comprehensive studies on chronic pancreatitis and its associations, such as the risk factors for pancreatic cancer, pancreatogenic diabetes, and newly diagnosed diabetes. The Consortium will focus on multidisciplinary research to understand the pathophysiology of chronic pancreatitis, chronic pain, pancreatic insufficiency, and diabetes-conferred pancreatic cancer risks. The Coordination and Data Management Center will oversee the administrative and data functions while establishing a bio-specimen repository for biomarker research.

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Opportunity ID: 268917

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: RFA-DK-14-028
Funding Opportunity Title:: Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Coordination and Data Management Center (CSCPDPC- CDMC) (U01)
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 93.393 — Cancer Cause and Prevention Research
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 1
Posted Date:: Oct 17, 2014
Last Updated Date::
Original Closing Date for Applications:: Apr 02, 2015
Current Closing Date for Applications:: Apr 02, 2015
Archive Date:: May 03, 2015
Estimated Total Program Funding:: $ 6,000,000
Award Ceiling:: $1,000,000
Award Floor:: $

Eligibility

Eligible Applicants:: Independent school districts
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name:: National Institutes of Health
Description:: This Funding Opportunity Announcement (FOA) invites U01 applications for the establishment of a clinical consortium, composed of one Coordination and Data Management Center (CDMC) and up to 9 Clinical Centers (CC), to conduct studies on chronic pancreatitis (CP) and factors that increase the risk of pancreatic cancer in patients (children and adults) with CP, pancreatogenic (type 3c) diabetes (T3cDM) and in patients with newly diagnosed diabetes.

The Consortium will form multi-disciplinary teams composed of members from the CCs and CDMC to undertake a comprehensive clinical, epidemiological and biological characterization of patients with CP (including those with Acute Recurrent Pancreatitis, ARP) to gain insight into the pathophysiology of chronic pancreatitis and its sequela: chronic pain, pancreatic insufficiency, T3cDM and the diabetes/pancreatic cancer association. The teams will also undertake studies on the development of pancreatic cancer in newly diagnosed diabetic patients.

Applications for the consortium Clinical Centers are being solicited via RFA-DK-14-027 “Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Clinical Centers (CSCPDPC-CCs) (U01)”.

To achieve the goal of a comprehensive characterization of evolving chronic pancreatitis and pancreatic cancer, the Coordinating and Data Management Center (CDMC) will take on the administrative and data collection/analysis functions and will be responsible for the conduct of all of the ongoing and future studies of the CCs.

In addition, a major collaborative effort within the Consortium will be the establishment of an annotated repository of bio-specimens (blood, pancreatic and duodenal juice, stools and when feasible pancreatic tissue) to allow for the identification and validation of biomarkers for risk stratification and/or early detection.

Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

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Packages

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Who Can Apply:
FORMS-C FORMS-C PKG00209169 Mar 02, 2015 Apr 02, 2015 View eRA Commons Help Desk Organization Applicants

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