National Institute on Aging: Plasticity and Mechanisms of Cognitive Remediation in Older Adults (R01)

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This institute is offering grants to develop interventions addressing age-related cognitive decline, focusing on testing intervention mechanisms, individual variation in responsiveness, and neural changes in older adults. Projects should incorporate a measurement framework to assess cognitive functioning improvements and must include testing in a randomized clinical trial. Applications should emphasize understanding adaptive plastic changes in the central nervous system resulting from the intervention. Closing date for submissions is March 4, 2014.

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Opportunity ID: 249676

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: RFA-AG-14-016
Funding Opportunity Title:: Plasticity and Mechanisms of Cognitive Remediation in Older Adults (R01)
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 93.213 — Research and Training in Complementary and Alternative Medicine
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 1
Posted Date:: Jan 03, 2014
Last Updated Date::
Original Closing Date for Applications:: Mar 04, 2014
Current Closing Date for Applications:: Mar 04, 2014
Archive Date:: Apr 04, 2014
Estimated Total Program Funding:: $ 3,000,000
Award Ceiling:: $
Award Floor:: $

Eligibility

Eligible Applicants:: City or township governments
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name:: National Institutes of Health
Description:: This funding opportunity announcement (FOA) solicits R01 grant applications from applicant organizations that propose to develop and implement interventions to remediate age-related cognitive decline. A crucial feature of these applications will be the embedding of the testing of the proposed intervention into a measurement framework that will: 1) help elucidate its mechanism of action; 2) identify specific individuals who are more likely or less likely to benefit from the intervention, and 3) examine whether adaptive plastic changes have occurred in the structure or function of the CNS as a result of the intervention, and whether these neural changes help explain the pattern of improvement seen in cognitive functioning. Although projects may include an observational component, the interventions developed should be tested in a randomized clinical trial (RCT).
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

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Packages

Assistance Listings Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions Who Can Apply:
FORMS-C Forms-C PKG00191491 Feb 04, 2014 Mar 04, 2014 View eRA Commons Help Desk Organization Applicants

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