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This grant aims to support research investigating the interaction of genetic and environmental factors in substance and alcohol use disorders. The focus is on deepening the understanding of the developmental trajectories, comorbid conditions, and phenotypic definitions of these disorders. By utilizing genetically informative approaches, researchers are encouraged to explore the interplay of genetic and environmental influences on the initiation, progression, adverse outcomes, and desistance of substance use disorders. The grant also seeks to advance knowledge of risk mechanisms and enhance possibilities for treatment, prevention, gene-finding, and molecular studies. Closing date for applications is September 7, 2014.
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Opportunity ID: 106255
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PA-11-236 |
| Funding Opportunity Title:: | Gene-Environment Interplay in Substance Use Disorders (R21) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Education |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Jul 19, 2011 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Sep 07, 2014 |
| Current Closing Date for Applications:: | Sep 07, 2014 |
| Archive Date:: | Oct 08, 2014 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $200,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | State governments |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism seek to stimulate and expand research on the interplay of genetic and environmental factors in the genesis, course, and outcomes of substance and alcohol use disorders (SUDs). Previous work in genetic epidemiology and molecular genetics has established that SUDs are highly heritable, developmental disorders with important genetic substrates. Building on these findings, new studies using genetically informative approaches are needed to elucidate the complex interplay of genetic and environmental factors in developmental trajectories of SUDs and comorbid conditions, deepen and refine phenotypic definitions of SUDs, and meet the methodologic challenges of the field. Such studies hold great potential to promote understanding of the true contributions of both genetic and environmental factors to initiation, progression, comorbidity, adverse outcomes, and desistance of SUDs; to elucidate mechanisms of risk; and to enhance opportunities for translation to treatment, prevention, gene-finding and molecular studies. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | |
| Competition ID: | ADOBE-FORMS-B1 |
| Competition Title: | ADOBE-FORMS-B1 |
| Opportunity Package ID: | PKG00065093 |
| Opening Date: | Sep 16, 2011 |
| Closing Date: | Sep 24, 2013 |
| Agency Contact Information:: | Grants Info |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Project/Performance Site Location(s) [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Cover Page Supplement [V1.4] PHS 398 Checklist [V1.3] |
| optional_forms |
Research & Related Budget [V1.1] R & R Subaward Budget Attachment(s) Form [V1.2] PHS Cover Letter [V1.2] PHS 398 Modular Budget [V1.1] |
Package No: 2
| Assistance Listings: | |
| Competition ID: | FORMS-C |
| Competition Title: | Use for due dates after 9/24/2013 |
| Opportunity Package ID: | PKG00181262 |
| Opening Date: | Sep 16, 2013 |
| Closing Date: | Sep 07, 2014 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Agency Contact Information: | Who Can Apply: |
|---|---|---|---|---|---|---|---|---|
| ADOBE-FORMS-B1 | ADOBE-FORMS-B1 | PKG00065093 | Sep 16, 2011 | Sep 24, 2013 | View | Grants Info | Organization Applicants |
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Agency Contact Information: | Who Can Apply: |
|---|---|---|---|---|---|---|---|---|
| FORMS-C | Use for due dates after 9/24/2013 | PKG00181262 | Sep 16, 2013 | Sep 07, 2014 | View | eRA Commons Help Desk | Organization Applicants |
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