This grant aims to support institutions and organizations in investigating brain processes in humans related to how aversive events influence behavior. The National Institute on Drug Abuse seeks to stimulate clinical neuroscience research on negative reinforcement and avoidance learning, with a focus on understanding the brain regions and processes involved in minimizing aversive outcomes. Projects may include exploratory studies or the development of new tasks to target specific brain processing areas affected by negative reinforcement. Research can be conducted in healthy individuals, substance-abusing populations, or those at risk for substance abuse, as long as they contribute to advancing the understanding of substance abuse.
Opportunity ID: 43305
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-09-009 |
| Funding Opportunity Title: | Brain Imaging Studies of Negative Reinforcement in Humans (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Feb 19, 2009 |
| Current Closing Date for Applications: | Feb 19, 2009 |
| Archive Date: | Mar 22, 2009 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments County governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Independent school districts Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA issued by National Institute on Drug Abuse, National Institutes of Health, solicits Exploratory/Developmental Grant (R21) applications from institutions/ organizations that propose to investigate brain processes in humans underlying how aversive events control behavior in order to stimulate a program of clinical neuroscience research on negative reinforcement / avoidance learning.On the basis of pre-clinical studies, negative reinforcement has re-emerged as a contributing factor in the basic processes of substance abuse.The range of processes engaged by the human brain to avoid aversive outcomes are much less well understood than that of brain processes engaged by positive outcomes. For the purpose of this FOA negative reinforcement and avoidance learning are considered synonymous and refer to behaviors and cognitive strategies that are learned and maintained in order to minimize or eliminate the occurrence of aversive events. Aversive events may be either environmental stimuli or internal states. Applications for this FOA are expected to propose exploratory, hypotheses-generating or proof of concept studies regarding the brain regions or processes in humans that underlie avoidance learning including behaviors and cognitive strategies maintained by negative reinforcement. This FOA is also appropriate for the development of new tasks in humans that may be used in future brain imaging studies to target specific brain processing areas affected by negative reinforcement/avoidance learning. The studies proposed in response to this FOA may be conducted in healthy individuals, substance-abusing populations (current or abstinent) or individuals at risk for substance abuse.However, all applications must address how the proposed investigations are relevant to advancing the understanding of substance abuse. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.279 | ADOBE-FORMS-A | Adobe-Forms-A | PKG00009590 | Jan 19, 2009 | Feb 26, 2009 | View |
Package 1
Mandatory forms
43305 RR_SF424-1.1.pdf
43305 RR_KeyPersonExpanded-1.1.pdf
43305 RR_OtherProjectInfo-1.1.pdf
43305 RR_PerformanceSite-1.1.pdf
43305 PHS398_CoverPageSupplement-1.1.pdf
43305 PHS398_ResearchPlan-1.1.pdf
43305 PHS398_Checklist-1.1.pdf
Optional forms
43305 PHS398_CoverLetter-1.1.pdf
43305 PHS398_ModularBudget-1.1.pdf
43305 RR_Budget-1.1.pdf
43305 RR_SubawardBudget-1.2.pdf
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