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This grant from the National Institute on Drug Abuse aims to support research investigating the impact of inflammasomes on the neurological effects of drug abuse and HIV infection. By understanding how inflammasomes contribute to immune activation in the context of substance abuse and HIV, researchers may uncover new therapeutic targets for addressing neuroinflammation and immune dysregulation. Applications are open until March 16, 2023.
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Opportunity ID: 344372
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-DA-24-003 |
| Funding Opportunity Title:: | Targeting Inflammasomes in Substance Abuse and HIV (R01 Clinical Trial Not Allowed) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Education |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Nov 03, 2022 |
| Last Updated Date:: | Nov 03, 2022 |
| Original Closing Date for Applications:: | Mar 16, 2023 |
| Current Closing Date for Applications:: | Mar 16, 2023 |
| Archive Date:: | Apr 21, 2023 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Independent school districts |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The scientific objective of this Funding Opportunity Announcement is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat neuroinflammation and immune dysregulation aroused in these processes. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 | Nov 03, 2022 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | |
| Competition ID: | FORMS-H |
| Competition Title: | Use for due dates on or after January 25, 2023 |
| Opportunity Package ID: | PKG00277928 |
| Opening Date: | Feb 16, 2023 |
| Closing Date: | Mar 16, 2023 |
| Agency Contact Information:: | eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V5.0] PHS 398 Cover Page Supplement [V5.0] Research And Related Other Project Information [V1.4] Project/Performance Site Location(s) [V4.0] Research and Related Senior/Key Person Profile (Expanded) [V4.0] PHS 398 Research Plan [V5.0] PHS Human Subjects and Clinical Trials Information [V3.0] |
| optional_forms |
Research & Related Budget [V3.0] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V3.0] PHS 398 Modular Budget [V1.2] PHS Assignment Request Form [V3.0] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277928 | Feb 16, 2023 | Mar 16, 2023 | View | eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ | Organization Applicants |
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