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The NIH is offering a grant to investigate the epigenetic modifications in gametes and embryos post-exposure to environmental factors. This grant aims to create a comprehensive reference epigenome for male and female gametes, identify affected genes, and analyze resulting phenotypes in offspring. The focus is on understanding transgenerational inheritance and developmental origins of health and disease. Applications from the scientific community are encouraged to contribute to building an atlas of epigenetic changes during spermatogenesis, oogenesis, and pre-implantation embryo development. The closing date for applications is January 30, 2015.
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Opportunity ID: 246694
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PAR-13-385 |
| Funding Opportunity Title:: | Developmental Origins of Health and Disease (DOHaD): Epigenetic Modification in Gametogenesis and Transgenerational Inheritance (R01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 2 |
| Posted Date:: | Nov 05, 2013 |
| Last Updated Date:: | Nov 20, 2013 |
| Original Closing Date for Applications:: | Jan 30, 2015 |
| Current Closing Date for Applications:: | Jan 30, 2015 |
| Archive Date:: | Mar 02, 2015 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $250,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support the development of comprehensive reference epigenomes for male and female gametes, and pre-implantation embryos after exposure to a particular environmental factor/insult. What is envisioned is the establishment of a compendium/atlas annotating epigenetic changes during various stages of spermatogenesis, oogenesis, and pre-implantation embryo development, the identification of the affected genes, and the characterization of any resulting phenotype in the offspring. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 2 | Added CFDA# per NIEHS participation | Nov 20, 2013 |
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.865 |
| Competition ID: | FORMS-C |
| Competition Title: | Forms-C |
| Opportunity Package ID: | PKG00188692 |
| Opening Date: | Dec 30, 2013 |
| Closing Date: | Jan 30, 2015 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.865 | FORMS-C | Forms-C | PKG00188692 | Dec 30, 2013 | Jan 30, 2015 | View | eRA Commons Help Desk | Organization Applicants |
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