The National Cancer Institute (NCI) offers funding to support The Cancer Genome Atlas (TCGA) research network aiming to provide genomic catalogs of alterations in human cancers, aiding in the development of new diagnostic tools, treatment strategies, and drug targets. Genome Characterization Centers (GCCs) will identify genomic aberrations, while Genome Data Analysis Centers (GDACs) will analyze and integrate data, develop bioinformatics tools, and perform advanced analyses. Prior TCGA involvement not required; institutions and individuals are encouraged to apply. Applications for GCCs, GDACs, or both are accepted with specified restrictions. Closing date for submissions is March 13, 2009.
Opportunity ID: 44611
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-09-010 |
| Funding Opportunity Title: | Genome Characterization Centers and Genome Data Analysis Centers for The Cancer Genome Atlas Research Network (TCGA)[U24] |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 07, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 13, 2009 |
| Current Closing Date for Applications: | Mar 13, 2009 |
| Archive Date: | Apr 13, 2009 |
| Estimated Total Program Funding: | $18,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Non-domestic (non-U.S.) Entities (Foreign Organizations). |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This funding opportunity announcement (FOA) is designed to support The Cancer Genome Atlas (TCGA) research network. The overall goal of this phase of the TCGA initiative is to provide genome-wide catalogs of genomic alterations in 20-25 different types of human cancer that could be used to identify and accelerate the development of new diagnostic and prognostic markers, new targets for pharmaceutical interventions, and new cancer prevention and treatment strategies.Under this FOA, the NCI solicits applications for two types of centers. (1) Genome Characterization Centers (GCCs); and (2) Genome Data Analysis Centers (GDACs, that must be oriented on one of two permissible types of analytical pipelines). An applicant/institution may submit one application for either type of centers or two applications for two different types (with certain restrictions regarding subtypes of GDACs). GCCs will utilize novel high-throughput, high resolution technologies to comprehensively (i.e., genome-wide) detect genomic, epigenomic and transcriptome aberrations including: alterations in chromosome segment copy numbers, translocations, loss of heterozygosity, altered DNA methylation patterns and changes in gene expression, which may play a role in cancer. GDACs will focus on the integration and analysis of data generated by the GCCs and other TCGA components, development of innovative bioinformatic and computational tools and the performance of advanced bioinformatic analyses including, but not limited to: systems biology approaches to discovery, pathway analysis models, and integrative data analysis methods with accompanying visualization tools to identify complex genomic changes; and integrated cancer biology and translational discovery models that will increase our understanding of cancer as a disease process.Prior contribution to the TCGA Pilot Project is not required and all qualified institutions and individuals are encouraged to apply to this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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