The National Cancer Institute is offering a grant opportunity for novel technologies focusing on capturing and enriching exfoliated abnormal cells and tumor-derived sub-cellular material from body fluids for biomarker studies. This grant aims to develop new methods to detect small numbers of exfoliated tumor cells in biological fluids. The NIH Exploratory/Developmental (R21) grant mechanism is used, with an anticipated two to three awards and a project period not exceeding 2 years. Eligible entities include for-profit and non-profit organizations, universities, hospitals, and various government agencies. Applications must be submitted by Sep 07, 2009.
Opportunity ID: 43721
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-06-499 |
| Funding Opportunity Title: | Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis(R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Current Closing Date for Applications: | Sep 07, 2009 Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Oct 07, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Private institutions of higher education Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Small businesses Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NCI solicits grant applications aimed at the development of novel technologies for capturing, enriching, and preserving exfoliated abnormal cells from body fluids or effusions as well as methods for concentrating the tumor-derived sub-cellular material for use in biomarker studies. In body fluids, such as sputum, exfoliated tumor cells are a minor component compared to normal cells. As a result, the detection of exfoliated abnormal cells by routine cytopathology is often limited by the small number of atypical cells present in a given specimen. New enrichment methods are necessary to facilitate the detection of small numbers of exfoliated tumor cells and tumor-derived sub-cellular materials in biological fluids. This funding opportunity announcement (FOA) will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with two FOAs of similar scientific scope that solicit applications under the SBIR and STTR mechanisms RFA (RFA-CA-07-027 and RFA-CA-07-028, respectively). Please refer to the NIH Guide Notice NOT-CA-06-034 (http://grants.nih.gov/grants/guide/notice-files/NOT-CA-06-034.html) for the cross-comparison and the outline of the characteristics and requirements for all three partner FOAs. The anticipated number of awards is two to three. There are no set-aside funds for this FOA. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over an R21 2-year period, with no more than $200,000 in direct costs allowed in any single year. Eligible Organizations: For profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals and laboratories; units of State and local governments; eligible agencies of the Federal government; domestic or foreign institutions/organizations; faith-based or community-based organizations; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); and Indian/Native American Tribally Designated Organization. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-06-499.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Archive Date has been updated due to Expiration/Closing Date change. | – | |
| Dec 05, 2008 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-06-499 |
| Funding Opportunity Title: | Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis(R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Current Closing Date for Applications: | Sep 07, 2009 Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Oct 07, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Private institutions of higher education Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Small businesses Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NCI solicits grant applications aimed at the development of novel technologies for capturing, enriching, and preserving exfoliated abnormal cells from body fluids or effusions as well as methods for concentrating the tumor-derived sub-cellular material for use in biomarker studies. In body fluids, such as sputum, exfoliated tumor cells are a minor component compared to normal cells. As a result, the detection of exfoliated abnormal cells by routine cytopathology is often limited by the small number of atypical cells present in a given specimen. New enrichment methods are necessary to facilitate the detection of small numbers of exfoliated tumor cells and tumor-derived sub-cellular materials in biological fluids. This funding opportunity announcement (FOA) will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with two FOAs of similar scientific scope that solicit applications under the SBIR and STTR mechanisms RFA (RFA-CA-07-027 and RFA-CA-07-028, respectively). Please refer to the NIH Guide Notice NOT-CA-06-034 (http://grants.nih.gov/grants/guide/notice-files/NOT-CA-06-034.html) for the cross-comparison and the outline of the characteristics and requirements for all three partner FOAs. The anticipated number of awards is two to three. There are no set-aside funds for this FOA. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over an R21 2-year period, with no more than $200,000 in direct costs allowed in any single year. Eligible Organizations: For profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals and laboratories; units of State and local governments; eligible agencies of the Federal government; domestic or foreign institutions/organizations; faith-based or community-based organizations; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); and Indian/Native American Tribally Designated Organization. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-06-499.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-06-499 |
| Funding Opportunity Title: | Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis(R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Aug 01, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses For profit organizations other than small businesses Private institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Special district governments Native American tribal governments (Federally recognized) County governments Independent school districts City or township governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NCI solicits grant applications aimed at the development of novel technologies for capturing, enriching, and preserving exfoliated abnormal cells from body fluids or effusions as well as methods for concentrating the tumor-derived sub-cellular material for use in biomarker studies. In body fluids, such as sputum, exfoliated tumor cells are a minor component compared to normal cells. As a result, the detection of exfoliated abnormal cells by routine cytopathology is often limited by the small number of atypical cells present in a given specimen. New enrichment methods are necessary to facilitate the detection of small numbers of exfoliated tumor cells and tumor-derived sub-cellular materials in biological fluids. This funding opportunity announcement (FOA) will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with two FOAs of similar scientific scope that solicit applications under the SBIR and STTR mechanisms RFA (RFA-CA-07-027 and RFA-CA-07-028, respectively). Please refer to the NIH Guide Notice NOT-CA-06-034 (http://grants.nih.gov/grants/guide/notice-files/NOT-CA-06-034.html) for the cross-comparison and the outline of the characteristics and requirements for all three partner FOAs. The anticipated number of awards is two to three. There are no set-aside funds for this FOA. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over an R21 2-year period, with no more than $200,000 in direct costs allowed in any single year. Eligible Organizations: For profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals and laboratories; units of State and local governments; eligible agencies of the Federal government; domestic or foreign institutions/organizations; faith-based or community-based organizations; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); and Indian/Native American Tribally Designated Organization. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-06-499.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00009069 | Dec 05, 2008 | Sep 07, 2009 | View |
Package 1
Mandatory forms
43721 RR_SF424-1.1.pdf
43721 RR_OtherProjectInfo-1.1.pdf
43721 RR_PerformanceSite-1.1.pdf
43721 PHS398_CoverPageSupplement-1.1.pdf
43721 PHS398_ResearchPlan-1.1.pdf
43721 PHS398_Checklist-1.1.pdf
Optional forms
43721 PHS398_CoverLetter-1.1.pdf
43721 PHS398_ModularBudget-1.1.pdf
43721 RR_Budget-1.1.pdf
43721 RR_SubawardBudget-1.2.pdf
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