The National Cancer Institute (NCI) is offering a grant to support research investigating the roles of the mucosal immune system and immunoregulatory cells in gastrointestinal carcinogenesis. This grant aims to enhance understanding of how the gastrointestinal microenvironment influences immune responses linked to inflammatory disease-associated cancer development. Researchers can apply for the NIH Research Project Grant (R01) award mechanism. The ultimate goal is to comprehensively examine the involvement of innate and adaptive immune responses in gastrointestinal cancer. Funding is subject to availability and the submission of high-quality applications.
Opportunity ID: 43844
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-07-256 |
| Funding Opportunity Title: | Immunoregulation of Gastrointestinal Carcinogenesis (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Current Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Jun 01, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses Native American tribal governments (Federally recognized) County governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments City or township governments State governments Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -Purpose. This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), solicits grant applications from researchers interested in the investigations of two aspects of gastrointestinal carcinogenesis, which include: (1) the roles of the mucosal immune system in initiating and maintaining inflammatory responses that contribute to the development of premalignant and malignant gastrointestinal cancers; and/or (2) the molecular mechanism(s) by which immunoregulatory cells dampen inflammation and decrease tumorigenesis. Applications submitted in response to this FOA should be focused on research that will increase our understanding of how the unique gastrointestinal microenvironment shapes mucosal immune responses in the setting of inflammatory disease-associated carcinogenesis. The ultimate goal of this scientific initiative is to generate a comprehensive understanding of how the innate and adaptive immune responses participate in gastrointestinal carcinogenesis. -Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism and runs in parallel with an FOA of identical scientific scope, PA-06-290, that solicits applications under the Exploratory/Developmental Grant (R21) award mechanism. -Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-07-256.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00009192 | Dec 05, 2008 | May 07, 2009 | View |
Package 1
Mandatory forms
43844 RR_SF424-1.1.pdf
43844 RR_KeyPersonExpanded-1.1.pdf
43844 RR_OtherProjectInfo-1.1.pdf
43844 RR_PerformanceSite-1.1.pdf
43844 PHS398_CoverPageSupplement-1.1.pdf
43844 PHS398_ResearchPlan-1.1.pdf
43844 PHS398_Checklist-1.1.pdf
Optional forms
43844 PHS398_CoverLetter-1.1.pdf
43844 PHS398_ModularBudget-1.1.pdf
43844 RR_Budget-1.1.pdf
43844 RR_SubawardBudget-1.2.pdf
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