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The National Heart, Lung, and Blood Institute (NHLBI) is offering the Phase 1 Research Project Grant (R01) for the development of novel molecular imaging reagents and technologies targeting lung health and diseases. Researchers will identify molecular targets, create probes, and validate them in cells and animal models. This grant aims to enable early disease detection, noninvasive monitoring, and improved drug delivery for lung diseases, with a Phase II for human studies in the future. Applications for both phases are welcome, with a vision to enhance lung disease diagnosis and treatment.
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Opportunity ID: 129117
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-HL-12-036 |
| Funding Opportunity Title:: | Molecular Imaging of the Lung- Phase 1 (R01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.838 — Lung Diseases Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Oct 24, 2011 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Feb 01, 2012 |
| Current Closing Date for Applications:: | Feb 01, 2012 |
| Archive Date:: | Mar 03, 2012 |
| Estimated Total Program Funding:: | $ 2,800,000 |
| Award Ceiling:: | $250,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | For profit organizations other than small businesses |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | This FOA, issued by the National Heart, Lung and Blood Institute (NHLBI), National Institute of Health, invites Research Project Grant (R01) applications to develop novel in vivo imaging reagents and technologies such as molecular probes that target pathways or cells involved in development and pathobiology of pulmonary diseases. In Phase I investigators will identify appropriate molecular targets with relevance to lung health and diseases, develop the appropriate molecular probes, in combination with innovative imaging approaches, and validate the developed probes in cells and in vivo animal models. NHLBI anticipates announcing a companion FOA for a Phase II that will be released at a later date, to support studies to extend molecular imaging methods to human studies for clinical applications in lung disease. Both phases will be open competitions. The long-term goal is to use molecular imaging to facilitate early detection and diagnosis of lung disease, enable noninvasive monitoring of lung disease progression and prognosis, and accelerate progress in cell-specific drug delivery and therapies. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.838 |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | ADOBE-FORMS-B2 |
| Opportunity Package ID: | PKG00084035 |
| Opening Date: | Jan 01, 2012 |
| Closing Date: | Feb 01, 2012 |
| Agency Contact Information:: | Grants Info |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.838 | ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00084035 | Jan 01, 2012 | Feb 01, 2012 | View | Grants Info | Organization Applicants |
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