NIDDK Grant for Lead Optimization and Pre-Clinical Development of Therapeutic Candidates (STTR R41/R42)

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NIDDK is offering a grant to support lead optimization and preclinical development of new therapies for diseases falling within its mission. This grant includes Phase I for preliminary steps in the process and Phase II for advanced projects, aiming to submit applications to the FDA. Proposals should outline defined milestones and timelines, with key decision points. Closing date for applications is January 7, 2017.

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Opportunity ID: 249654

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: PA-14-054
Funding Opportunity Title:: Lead Optimization and Pre-Clinical Development of Therapeutic Candidates for Diseases of Interest to NIDDK (STTR (R41/R42))
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Food and Nutrition
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 1
Posted Date:: Jan 02, 2014
Last Updated Date::
Original Closing Date for Applications:: Jan 07, 2017
Current Closing Date for Applications:: Jan 07, 2017
Archive Date:: Feb 07, 2017
Estimated Total Program Funding::
Award Ceiling:: $
Award Floor:: $

Eligibility

Eligible Applicants:: Small businesses
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Additional Information

Agency Name:: National Institutes of Health
Description:: The goal of this Funding Opportunity Announcement (FOA) is to support lead optimization and preclinical development of new therapies for diseases within the mission of the NIDDK. Phase I supports preliminary steps in the process for lead optimization or preclinical development of therapeutics. Phase II supports lead optimization and preclinical development of lead candidates and projects must be sufficiently advanced such that an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application to the Food and Drug Administration (FDA) can be submitted by the end of a Phase II or IIB project. Applications are expected to have defined Milestones and Timelines detailing how the project will move forward with identified key Go/No Go decision points.
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings: 93.847
Competition ID: ADOBE-FORMS-B2
Competition Title: Adobe-Forms-B2
Opportunity Package ID: PKG00191470
Opening Date: Mar 05, 2014
Closing Date: Sep 07, 2014
Agency Contact Information:: eRA Commons Help Desk
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V1.2]
Project/Performance Site Location(s) [V1.4]
Research And Related Other Project Information [V1.3]
Research And Related Senior/Key Person Profile (Expanded) [V1.2]
Research & Related Budget [V1.1]
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2]
PHS 398 Cover Page Supplement [V1.4]
PHS 398 Research Plan [V1.3]
PHS 398 Checklist [V1.3]
SBIR/STTR_Information [V1.1]
optional_forms PHS Cover Letter [V1.2]

Package No: 2

Assistance Listings:
Competition ID: FORMS-C
Competition Title: Use for due dates on or after August 5, 2014
Opportunity Package ID: PKG00196573
Opening Date: Mar 05, 2014
Closing Date: Jun 08, 2016
Agency Contact Information:: eRA Commons Help Desk
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V2.0]
SBIR/STTR_Information [V1.1]
Research and Related Senior/Key Person Profile (Expanded) [V2.0]
Research And Related Other Project Information [V1.3]
Research & Related Budget [V1.3]
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3]
Project/Performance Site Location(s) [V2.0]
PHS 398 Research Plan [V2.0]
PHS 398 Cover Page Supplement [V2.0]
optional_forms Planned Enrollment Report [V1.0]
PHS 398 Cumulative Inclusion Enrollment Report [V1.0]

Package No: 3

Assistance Listings:
Competition ID: FORMS-D
Competition Title: Use for due dates on or after May 25, 2016
Opportunity Package ID: PKG00224045
Opening Date: Aug 05, 2016
Closing Date: Jan 07, 2017
Agency Contact Information:: eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V2.0]
PHS 398 Cover Page Supplement [V3.0]
Research And Related Other Project Information [V1.3]
Project/Performance Site Location(s) [V2.0]
Research and Related Senior/Key Person Profile (Expanded) [V2.0]
Research & Related Budget [V1.3]
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3]
PHS 398 Research Plan [V3.0]
SBIR/STTR_Information [V1.1]
optional_forms PHS Inclusion Enrollment Report [V1.0]
PHS Assignment Request Form [V1.0]

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