The National Institute of Health (NIH) is offering a grant opportunity for researchers to investigate the immunoregulation of gastrointestinal carcinogenesis. The focus is on understanding the roles of the mucosal immune system in inflammatory responses contributing to gastrointestinal cancers, as well as the molecular mechanisms regulating inflammation and tumorigenesis. The goal is to explore how the gastrointestinal microenvironment influences immune responses in carcinogenesis. This grant uses the Exploratory/Developmental (R21) mechanism with a 2-year project period and total direct costs limited to $275,000. Eligible organizations include various institutions, and individuals with the necessary expertise are encouraged to apply, with the closing date on May 07, 2009.
Opportunity ID: 43673
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-06-290 |
| Funding Opportunity Title: | Immunoregulation of Gastrointestinal Carcinogenesis (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Current Closing Date for Applications: | May 07, 2009 Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Jun 07, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Special district governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government are eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -This Funding Opportunity Announcement (FOA) solicits innovative Exploratory/Developmental (R21) grant applications from researchers interested in the investigations of two aspects of gastrointestinal carcinogenesis: (i) the roles of the mucosal immune system in initiating and maintaining inflammatory responses that contribute to the development of pre-malignant and malignant gastrointestinal cancers; and/or (ii) the molecular mechanism(s) by which immunoregulatory cells dampen inflammation and decrease tumorigenesis. Applications submitted in response to this FOA should be focused on research that will increase our understanding of how the unique gastrointestinal microenvironment shapes mucosal immune responses in the setting of inflammatory disease-associated carcinogenesis. The ultimate goal of this scientific initiative is to generate a comprehensive understanding of how the innate and adaptive immune responses participate in gastrointestinal carcinogenesis. -This FOA will utilize the Exploratory/Developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope, (PA-06-289), that solicits applications under the R01 award mechanism. -The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over a 2-year period, with no more than $200,000 in direct costs allowed in any single year. -Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. -Eligible organizations: For-profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals and laboratories; units of State governments; units of State Tribal governments; units of local governments; units of local Tribal governments; eligible institutions of the Federal government; Domestic institutions; Foreign institutions; and faith-based or community-based organizations. -Eligible Project Directors/Principal Investigators (PD/PIs): Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with his/her institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. -Applicants may submit more than one application, provided each application is scientifically distinct. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-06-290.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Archive Date has been updated due to Expiration/Closing Date change. | – | |
| Dec 05, 2008 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-06-290 |
| Funding Opportunity Title: | Immunoregulation of Gastrointestinal Carcinogenesis (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Current Closing Date for Applications: | May 07, 2009 Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Jun 07, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Special district governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government are eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -This Funding Opportunity Announcement (FOA) solicits innovative Exploratory/Developmental (R21) grant applications from researchers interested in the investigations of two aspects of gastrointestinal carcinogenesis: (i) the roles of the mucosal immune system in initiating and maintaining inflammatory responses that contribute to the development of pre-malignant and malignant gastrointestinal cancers; and/or (ii) the molecular mechanism(s) by which immunoregulatory cells dampen inflammation and decrease tumorigenesis. Applications submitted in response to this FOA should be focused on research that will increase our understanding of how the unique gastrointestinal microenvironment shapes mucosal immune responses in the setting of inflammatory disease-associated carcinogenesis. The ultimate goal of this scientific initiative is to generate a comprehensive understanding of how the innate and adaptive immune responses participate in gastrointestinal carcinogenesis. -This FOA will utilize the Exploratory/Developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope, (PA-06-289), that solicits applications under the R01 award mechanism. -The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over a 2-year period, with no more than $200,000 in direct costs allowed in any single year. -Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. -Eligible organizations: For-profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals and laboratories; units of State governments; units of State Tribal governments; units of local governments; units of local Tribal governments; eligible institutions of the Federal government; Domestic institutions; Foreign institutions; and faith-based or community-based organizations. -Eligible Project Directors/Principal Investigators (PD/PIs): Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with his/her institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. -Applicants may submit more than one application, provided each application is scientifically distinct. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-06-290.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-06-290 |
| Funding Opportunity Title: | Immunoregulation of Gastrointestinal Carcinogenesis (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 05, 2008 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | – Multiple Receipt Dates – See Link to Full Announcement for details. |
| Archive Date: | Apr 01, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education County governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments Private institutions of higher education Special district governments State governments |
| Additional Information on Eligibility: | Foreign institutions are eligible to apply. Eligible agencies of the Federal Government are eligible to apply. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -This Funding Opportunity Announcement (FOA) solicits innovative Exploratory/Developmental (R21) grant applications from researchers interested in the investigations of two aspects of gastrointestinal carcinogenesis: (i) the roles of the mucosal immune system in initiating and maintaining inflammatory responses that contribute to the development of pre-malignant and malignant gastrointestinal cancers; and/or (ii) the molecular mechanism(s) by which immunoregulatory cells dampen inflammation and decrease tumorigenesis. Applications submitted in response to this FOA should be focused on research that will increase our understanding of how the unique gastrointestinal microenvironment shapes mucosal immune responses in the setting of inflammatory disease-associated carcinogenesis. The ultimate goal of this scientific initiative is to generate a comprehensive understanding of how the innate and adaptive immune responses participate in gastrointestinal carcinogenesis. -This FOA will utilize the Exploratory/Developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope, (PA-06-289), that solicits applications under the R01 award mechanism. -The total project period for an application submitted in response to this funding opportunity may not exceed 2 years. Direct costs are limited to $275,000 over a 2-year period, with no more than $200,000 in direct costs allowed in any single year. -Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. -Eligible organizations: For-profit organizations; non-profit organizations; public or private institutions, such as universities, colleges, hospitals and laboratories; units of State governments; units of State Tribal governments; units of local governments; units of local Tribal governments; eligible institutions of the Federal government; Domestic institutions; Foreign institutions; and faith-based or community-based organizations. -Eligible Project Directors/Principal Investigators (PD/PIs): Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with his/her institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. -Applicants may submit more than one application, provided each application is scientifically distinct. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-06-290.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00009020 | Dec 05, 2008 | May 07, 2009 | View |
Package 1
Mandatory forms
43673 RR_SF424-1.1.pdf
43673 RR_OtherProjectInfo-1.1.pdf
43673 RR_PerformanceSite-1.1.pdf
43673 PHS398_CoverPageSupplement-1.1.pdf
43673 PHS398_ResearchPlan-1.1.pdf
43673 PHS398_Checklist-1.1.pdf
Optional forms
43673 PHS398_CoverLetter-1.1.pdf
43673 PHS398_ModularBudget-1.1.pdf
43673 RR_Budget-1.1.pdf
43673 RR_SubawardBudget-1.2.pdf
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