NIH Grant: Investigating Impact of Addictive Substances on Brain Developmental Trajectories

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NIH offers a grant to investigate the effects of addictive substances on developmental trajectories of CNS cells and circuits using innovative quantification methods. This grant aims to identify critical developmental windows and cellular mechanisms impacted by in utero or postnatal substance exposure. Projects will focus on whole brains or specific circuits of clinical relevance and complement data from human longitudinal neuroimaging studies like the ABCD study. Applications are accepted until Feb 02, 2023.

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Opportunity ID: 344404

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General Information

Document Type:: Grants Notice
Funding Opportunity Number:: RFA-DA-23-036
Funding Opportunity Title:: Investigating the Effects of Addictive Substances on Brain Developmental Trajectories Using Innovative Scalable Methods for Quantification of Cell Identity, Lineage and Connectivity (R01 – Clinical Trial Not Allowed)
Opportunity Category:: Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity:: Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s):: 93.279 — Drug Abuse and Addiction Research Programs
Cost Sharing or Matching Requirement:: No
Version:: Synopsis 1
Posted Date:: Nov 08, 2022
Last Updated Date:: Nov 08, 2022
Original Closing Date for Applications:: Feb 02, 2023
Current Closing Date for Applications:: Feb 02, 2023
Archive Date:: Mar 10, 2023
Estimated Total Program Funding::
Award Ceiling:: $700,000
Award Floor:: $

Eligibility

Eligible Applicants:: Small businesses
Additional Information on Eligibility:: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name:: National Institutes of Health
Description:: This Funding Opportunity Announcement (FOA) will support projects that investigate the effects of addictive substances on developmental trajectories of molecularly-defined CNS cells and circuits. Emphasis is on carrying out systematic and highly granular quantitative characterizations of the impact of in utero and/or postnatal substance exposure on the numbers, spatial distribution and connectivity of molecularly-defined cells, across whole brains or within distributed circuits of clinical relevance. The ultimate goals of the program are to identify critical developmental windows and cellular mechanisms mediating the protracted developmental impact of addictive substances, and will inform clinical practice, by complementing the data from human longitudinal neuroimaging studies such as the ABCD study.?
Link to Additional Information::
Grantor Contact Information:: If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version Modification Description Updated Date
Synopsis 1 Nov 08, 2022

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID: FORMS-H
Competition Title: Use for due dates on or after January 25, 2023
Opportunity Package ID: PKG00278189
Opening Date: Jan 02, 2023
Closing Date: Feb 02, 2023
Agency Contact Information:: eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/
Who Can Apply:: Organization Applicants
mendatory_forms SF424 (R & R) [V5.0]
PHS 398 Cover Page Supplement [V5.0]
Research And Related Other Project Information [V1.4]
Project/Performance Site Location(s) [V4.0]
Research and Related Senior/Key Person Profile (Expanded) [V4.0]
PHS 398 Research Plan [V5.0]
PHS Human Subjects and Clinical Trials Information [V3.0]
optional_forms Research & Related Budget [V3.0]
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V3.0]
PHS 398 Modular Budget [V1.2]
PHS Assignment Request Form [V3.0]

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