The National Institutes of Health is offering grants to support the development of new toxicity assays for various organ toxicities and models for specific conditions resulting from exposures to chemicals, pollutants, biologics, and drugs. Emphasis is placed on innovative approaches such as high-throughput screening, molecular endpoints, and 3-dimensional organ models. Funding is available through the SBIR (R43/R44) grant mechanisms, with potential for Phase I, Phase II, and Fast-Track applications. Applicants are encouraged to utilize advanced technologies like proteomics, genomics, and computer modeling. The closing date for applications is September 7, 2009.
Opportunity ID: 44977
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-09-006 |
| Funding Opportunity Title: | Innovative Toxicity Assays of Pollutants, Therapeutics, and Drugs (SBIR [R43/R44]) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Environment Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 26, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2009 |
| Current Closing Date for Applications: | Sep 07, 2009 |
| Archive Date: | Oct 08, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | -Purpose. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involves the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. -Mechanism of Support. This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-007, which encourages applications under the Small Business Technology Transfer (STTR) (R41/R42) grant mechanisms. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-09-006.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00010187 | Jan 26, 2009 | Sep 07, 2009 | View |
Package 1
Mandatory forms
44977 RR_SF424-1.1.pdf
44977 RR_KeyPersonExpanded-1.1.pdf
44977 RR_OtherProjectInfo-1.1.pdf
44977 RR_PerformanceSite-1.1.pdf
44977 RR_Budget-1.1.pdf
44977 SBIR_STTR_Information-1.0.pdf
44977 PHS398_CoverPageSupplement-1.1.pdf
44977 PHS398_ResearchPlan-1.1.pdf
44977 PHS398_Checklist-1.1.pdf
Optional forms
44977 PHS398_CoverLetter-1.1.pdf
44977 RR_SubawardBudget-1.2.pdf
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