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This NIMH grant aims to support research on how the gut microbiome influences brain circuits relevant to mental health. Focus is placed on developmental studies investigating the early-life colonization’s impact on the central nervous system. Proposed research can involve model organisms or human cohorts. The goal is for investigator teams to develop hypothesis-driven studies and identify potential mechanisms for future research, aligning with NIMH’s mission to advance mental health understanding.
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Opportunity ID: 225913
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General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-MH-14-080 |
| Funding Opportunity Title:: | Gut-Microbiome-Brain Interactions and Mental Health (R21/R33) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 2 |
| Posted Date:: | Mar 08, 2013 |
| Last Updated Date:: | Oct 18, 2013 |
| Original Closing Date for Applications:: | Oct 10, 2013 |
| Current Closing Date for Applications:: | Nov 01, 2013 |
| Archive Date:: | Dec 01, 2013 |
| Estimated Total Program Funding:: | $ 2,000,000 |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | County governments |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | This Funding Opportunity Announcement (FOA) encourages research grant applications from institutions/organizations to investigate mechanisms by which the gut microbiome modulates the development and function of brain circuits that subserve behavioral functions of direct relevance to the mission of the NIMH.Because initial colonization of the gut by microbiota occurs early in life and may influence the subsequent development and modifiability of the central nervous system, developmental studies are of particular interest. Applicants may propose to use wild-type, gnotobiotic, or specific pathogen-free model organisms and/or human cohorts. With this FOA, the NIMH encourages investigator teams to initiate hypothesis-driven research in this cross-cutting research area and to identify promising mechanistic leads for future basic and translational research that will advance the mission of the NIMH. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 2 | Modified Archive Date based on new Expiration Date, per NOT-OD-14-003. | Oct 18, 2013 |
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.242 |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | Adobe-Forms-B2 |
| Opportunity Package ID: | PKG00169390 |
| Opening Date: | Sep 10, 2013 |
| Closing Date: | Sep 24, 2013 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Research & Related Budget [V1.1] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS Cover Letter [V1.2] |
Package No: 2
| Assistance Listings: | 93.242 |
| Competition ID: | FORMS-C |
| Competition Title: | Use for due dates after 9/24/2013. |
| Opportunity Package ID: | PKG00181210 |
| Opening Date: | Sep 16, 2013 |
| Closing Date: | Nov 01, 2013 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
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Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.242 | ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00169390 | Sep 10, 2013 | Sep 24, 2013 | View | eRA Commons Help Desk | Organization Applicants |
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| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.242 | FORMS-C | Use for due dates after 9/24/2013. | PKG00181210 | Sep 16, 2013 | Nov 01, 2013 | View | eRA Commons Help Desk | Organization Applicants |
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