PAR-23-311: NINDS Funding Opportunity for Small Businesses in Neurosciences

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The National Institutes of Health (NIH) has announced a grant opportunity, designated as PAR-23-311, aimed at Small Business Concerns (SBCs) in the field of neurosciences and neurological disorders. This funding opportunity is an initiative of the National Institute of Neurological Disorders and Stroke (NINDS) and seeks to support exploratory clinical trials that align with the institute’s mission and goals. The focus is on fostering innovative research in the development and evaluation of drugs, biologics, devices, diagnostics, and various therapies, including surgical, behavioral, and rehabilitation therapies.

Eligibility for this grant is specifically directed towards small businesses, emphasizing the NIH’s commitment to advancing scientific discoveries and innovations in the field of neurosciences through the Small Business Innovation Research (SBIR) program. This opportunity supports only SBIR Phase II and Fast-Track applications, providing a unique platform for small businesses to contribute to significant advancements in the understanding and treatment of neurological disorders. The closing date for applications is set for September 5, 2026, offering an extended period for interested small businesses to prepare and submit their proposals. This initiative represents an important step in encouraging small business participation in cutting-edge neurological research and development, potentially leading to breakthroughs in the treatment and management of various neurological conditions.

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Opportunity ID: 351149

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General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-23-311
Funding Opportunity Title: NINDS Exploratory Clinical Trials for Small Business (R43/R44 Clinical Trial Required)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards:
CFDA Number(s): 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Nov 27, 2023
Last Updated Date: Nov 27, 2023
Original Closing Date for Applications: Sep 05, 2026
Current Closing Date for Applications: Sep 05, 2026
Archive Date: Oct 11, 2026
Estimated Total Program Funding:
Award Ceiling: $
Award Floor: $

Eligibility

Eligible Applicants: Small businesses
Additional Information on Eligibility: Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Additional Information

Agency Name: National Institutes of Health
Description: (Reissue of PAR-21-266) The purpose of this funding opportunity announcement (FOA) is to provide a vehicle for Small Business Concerns (SBCs) submitting Small Business Innovation Research (SBIR) grant applications for investigator-initiated exploratory clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The projects must focus on products related to the mission and goals of the NINDS and may evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral or rehabilitation therapies. Only SBIR Phase II and Fast-Track applications are supported under this program. SBIR Phase I applications are only accepted as part of a Fast-track application.
Link to Additional Information: https://grants.nih.gov/grants/guide/pa-files/PAR-23-311.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information
grantsinfo@nih.gov

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